ARJUNA (Terminalia Arjuna) CARDIO COMFORT
ARJUNA (Terminalia Arjuna)
Part Used: the bark of a deciduous tree of originating from the lower Himalayas but found growing throughout India.
Traditional use: The Ayurvedic sage Vagbhatta (342 BC) was the first to describe Arjuna as a tonic. Used in India as a cardiotonic for over 1500 years. It is indicated for derangement of all three humours, vata, pitta and kapha.
---- and specifically for all conditions associated with cardiac failure including irregular heart beat, palpitations, mitral valve prolapse, coronary artery disease, hypertension and congestive heart failure.
----- It has a stimulant effect on the heart so is particularly useful for a weak heart. However, because it treats derangement of all three humours, it also strengthens the heart muscle – unlike digitalis or nitroglycerine that only strengthens and restores heart beat with no nutritive effect on the heart muscle itself.
The bark is useful as an anti-ischemic and cardioprotective agent in hypertension and in ischemic heart disease. It also has a tonic effect in cases of cirrhosis of the liver. It induces a drug-dependent decrease in blood pressure and heart rate. It has been reported to possess protective cardiovascular and hypolipidemic properties. It reduces the level of triglycerides and cholesterol and has been reported to enhance the synthesis of LDL-apoprotein (apoB). It inhibits the oxidation of LDL and accelerates the turnover of LDL-cholesterol in liver. This enhances the elimination of cholesterol from the body. The suppression of hepatic cholesterol biosynthesis by Terminalia arjuna is the mechanism responsible for a significant lowering of beta-lipoprotein lipids and the recovery of HDL components in hyperlipidemia.
In a study on the efficacy of the bark powder in treating congestive cardiac failure (CCF), over 40% of the cases showed marked improvement. CCF due to congenital anomaly of heart and valvular disease was also brought under control. 4 out of 9 cases of CCF due to chronic bronchitis were also relieved by the treatment. Arjuna relieved symptomatic complaints of essential hypertension viz. giddiness, insomnia, lassitude, headache and the inability to concentrate. Oral administration of an aqueous suspension of the bark powder reduces coagulation, bleeding and prothrombin time.
Terminalia's active constituents include tannins, triterpenoid saponins, flavonoids, gallic acid, ellagic acid, OPSs, phytosterols, calcium, magnesium, zinc, and copper. 1 Several studies have elucidated Terminalia's effects on various cardiac disorders including congestive heart failure, coronary artery disease, and hypertension. A study on its effects on stable and unstable angina patients found it effective for those with stable angina episodes and significant decrease in systolic blood pressure. 2
In a double-blind crossover study, twelve subjects with refractory chronic congestive heart failure (idiopathic dialated cardiomyopathy (n=10): previous myocardial infarction (n=1), or peripartum cardiomyopathy (n=1), received Terminalia arjuna , at a dose of 500 mg every eight hours, or placebo for two weeks, each treatment protocol separated by a two-week washout period, as an adjuvant to conventional therapy. Terminalia, compared to placebo, was associated with improvement in symptoms and signs of heart failure, decrease in echo-left ventricular and diastolic and end systolic volume indices, increase in left ventricular stroke volume index, and increase in left ventricular ejection fractions. A study with similar dosing on primarily post-myocardial infarction angina patients found improvements in cardiac function. Prolonged use resulted in no adverse side effects or signs of renal, hepatic, or hematological abnormalities. 3
Terminalia arjuna possesses antimutagenic ability.
In addition to its benefits for the heart, arjuna has also shown antimutagenic and anticarcinogenic effects.
Efficacy of Terminalia arjuna in chronic stable angina: a double-blind, placebo-controlled, crossover study comparing Terminalia arjuna with isosorbide mononitrate
Terminalia arjuna, an Indian medicinal plant, has been reported to have beneficial effects in patients with ischemic heart disease in a number of small, open studies. The bark extract (IPC-53) contains acids (arjunic acid, terminic acid), glicosides (arjunetin arjunosides I-IV), strong antioxidants (flavones, tannins, oligomeric proanthocyanidins), minerals, etc., and exhibits antifailure and anti-ischemic properties.
Fifty-eight males with chronic stable angina (NYHA class II-III) with evidence of provocable ischemia on treadmill exercise test received Terminalia arjuna (500 mg 8 hourly), isosorbide mononitrate (40 mg/daily), or a matching placebo for one week each, separated by a wash-out period of a t least three days in a randomized, double-blind, crossover design. They underwent clinical, biochemical and treadmill exercise evaluation at the end of each therapy which were compared during the three therapy periods.
Terminalia arjuna therapy was associated with significant decrease in the frequency of angina and need for isosorbide dinitrate (5.69+/-6.91 mg/week v. 18.22+/-9.29 mg/week during placebo therapy, p<0.005). The treadmill exercise test parameters improved significantly during therapy with Terminalia arjuna compared to those with placebo. Terminalia arjuna bark extract, 500 mg 8 hourly, given to patients with stable angina with provocable ischemia on treadmill exercise, led to improvement in clinical and treadmill exercise parameters as compared to placebo therapy. These benefits were similar to those observed with isosorbide mononitrate (40mg/day) therapy and the extract was well tolerated. By Michael Tierra L.Ac. AHG
Read More About Terminalia Arjuna and its benefits at http://www.ayurvediccure.com/arjuna.htm
Buy Terminalia Arjuna Supplements at http://www.ayurvediccure.com/arjuna.htm
Part Used: the bark of a deciduous tree of originating from the lower Himalayas but found growing throughout India.
Traditional use: The Ayurvedic sage Vagbhatta (342 BC) was the first to describe Arjuna as a tonic. Used in India as a cardiotonic for over 1500 years. It is indicated for derangement of all three humours, vata, pitta and kapha.
---- and specifically for all conditions associated with cardiac failure including irregular heart beat, palpitations, mitral valve prolapse, coronary artery disease, hypertension and congestive heart failure.
----- It has a stimulant effect on the heart so is particularly useful for a weak heart. However, because it treats derangement of all three humours, it also strengthens the heart muscle – unlike digitalis or nitroglycerine that only strengthens and restores heart beat with no nutritive effect on the heart muscle itself.
The bark is useful as an anti-ischemic and cardioprotective agent in hypertension and in ischemic heart disease. It also has a tonic effect in cases of cirrhosis of the liver. It induces a drug-dependent decrease in blood pressure and heart rate. It has been reported to possess protective cardiovascular and hypolipidemic properties. It reduces the level of triglycerides and cholesterol and has been reported to enhance the synthesis of LDL-apoprotein (apoB). It inhibits the oxidation of LDL and accelerates the turnover of LDL-cholesterol in liver. This enhances the elimination of cholesterol from the body. The suppression of hepatic cholesterol biosynthesis by Terminalia arjuna is the mechanism responsible for a significant lowering of beta-lipoprotein lipids and the recovery of HDL components in hyperlipidemia.
In a study on the efficacy of the bark powder in treating congestive cardiac failure (CCF), over 40% of the cases showed marked improvement. CCF due to congenital anomaly of heart and valvular disease was also brought under control. 4 out of 9 cases of CCF due to chronic bronchitis were also relieved by the treatment. Arjuna relieved symptomatic complaints of essential hypertension viz. giddiness, insomnia, lassitude, headache and the inability to concentrate. Oral administration of an aqueous suspension of the bark powder reduces coagulation, bleeding and prothrombin time.
Terminalia's active constituents include tannins, triterpenoid saponins, flavonoids, gallic acid, ellagic acid, OPSs, phytosterols, calcium, magnesium, zinc, and copper. 1 Several studies have elucidated Terminalia's effects on various cardiac disorders including congestive heart failure, coronary artery disease, and hypertension. A study on its effects on stable and unstable angina patients found it effective for those with stable angina episodes and significant decrease in systolic blood pressure. 2
In a double-blind crossover study, twelve subjects with refractory chronic congestive heart failure (idiopathic dialated cardiomyopathy (n=10): previous myocardial infarction (n=1), or peripartum cardiomyopathy (n=1), received Terminalia arjuna , at a dose of 500 mg every eight hours, or placebo for two weeks, each treatment protocol separated by a two-week washout period, as an adjuvant to conventional therapy. Terminalia, compared to placebo, was associated with improvement in symptoms and signs of heart failure, decrease in echo-left ventricular and diastolic and end systolic volume indices, increase in left ventricular stroke volume index, and increase in left ventricular ejection fractions. A study with similar dosing on primarily post-myocardial infarction angina patients found improvements in cardiac function. Prolonged use resulted in no adverse side effects or signs of renal, hepatic, or hematological abnormalities. 3
Terminalia arjuna possesses antimutagenic ability.
In addition to its benefits for the heart, arjuna has also shown antimutagenic and anticarcinogenic effects.
Efficacy of Terminalia arjuna in chronic stable angina: a double-blind, placebo-controlled, crossover study comparing Terminalia arjuna with isosorbide mononitrate
Terminalia arjuna, an Indian medicinal plant, has been reported to have beneficial effects in patients with ischemic heart disease in a number of small, open studies. The bark extract (IPC-53) contains acids (arjunic acid, terminic acid), glicosides (arjunetin arjunosides I-IV), strong antioxidants (flavones, tannins, oligomeric proanthocyanidins), minerals, etc., and exhibits antifailure and anti-ischemic properties.
Fifty-eight males with chronic stable angina (NYHA class II-III) with evidence of provocable ischemia on treadmill exercise test received Terminalia arjuna (500 mg 8 hourly), isosorbide mononitrate (40 mg/daily), or a matching placebo for one week each, separated by a wash-out period of a t least three days in a randomized, double-blind, crossover design. They underwent clinical, biochemical and treadmill exercise evaluation at the end of each therapy which were compared during the three therapy periods.
Terminalia arjuna therapy was associated with significant decrease in the frequency of angina and need for isosorbide dinitrate (5.69+/-6.91 mg/week v. 18.22+/-9.29 mg/week during placebo therapy, p<0.005). The treadmill exercise test parameters improved significantly during therapy with Terminalia arjuna compared to those with placebo. Terminalia arjuna bark extract, 500 mg 8 hourly, given to patients with stable angina with provocable ischemia on treadmill exercise, led to improvement in clinical and treadmill exercise parameters as compared to placebo therapy. These benefits were similar to those observed with isosorbide mononitrate (40mg/day) therapy and the extract was well tolerated. By Michael Tierra L.Ac. AHG
Read More About Terminalia Arjuna and its benefits at http://www.ayurvediccure.com/arjuna.htm
Buy Terminalia Arjuna Supplements at http://www.ayurvediccure.com/arjuna.htm
posted by Health Blog @ 3:30 PM
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