| The herb is also a great bitter tonic having detergent property. In medicine, it is known for its anti-inflammatory effects. Gymnema also improves digestion, and enhances the liver's performance. It can be used to treat a poor appetite and dyspepsia. The herb is also traditionally used to burn the body fats so it is also considered as anti-obesity drug.
- Great sugar regulator and hence it is best as diabetic support.
- Weight reducing or Obesity
- Inhibits inflammatory conditions
- Restores appetite
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Serving size: 2 Vegi caps
Servings per container: 30
Each 500 mg capsule contains: Meshshringi
Dosage: 1-2 Capsules two times a day after meal or or as directed by your health practitioner.
Though the herb Gymnema sylvestre has been used to treat a number of conditions, it is best known for its great ability to lower down blood glucose levels. Results from case-reports and studies in humans and animals reveal that the herb may work in several ways to help controlling both; type I diabetes and type II diabetes.
First, the acids present in Gymnema sylvestre seem to lower down the amounts of sugar that are absorbed from foods. As a result, blood glucose levels may not increase as much as usually they do after meals. Secondly, Gymnema sylvestre may stimulate the production of insulin in the body. Possibly, Gymnema sylvestre might be even promoting the pancreas to develop more beta cells those are the major source of insulin.
Gymnema may also make body cells more responsible to the insulin that is present in the bloodstream. Finally, several studies have indicated that chewing on the leaves of Gymnema sylvestre dulls the sense of taste for sweetened foods. Participants in studies tended to have fewer sweet-tasting foods and drinks after using Gymnema sylvestre.
In clinical studies of animals with diabetes, Gymnema sylvestre also approved to reduce body weight, blood cholesterol, and triglyceride levels. Although the proper reasons are not clear, Gymnema sylvestre is considered to be block to the absorption of dietary fats into the bloodstream. Maybe, more fats are then eliminated instead of getting stored in the body. Some individuals taking Gymnema sylvestre for diabetes has also noticed a reduction in cholesterol and/or weight, but no human studies of Gymnema sylvestre’s potential cholesterol-lowering or anti-obesity actions have been reported.
Gymnema sylvestre is herb that is widely used in India and some parts of Asia as a natural treatment for diabetes or “sweet urine.” The Gymnema’s active ingredient, gymnemic acid, is extracted from leaves and roots. This is considered to be agent that helps to lower and to balance blood glucose levels. The unique shape of gymnemic acid molecules are similar to that of glucose, enabling it to fill cell receptors in the lining of the bowels and thereby preventing uptake of sugar molecules.
The U.S. National Library of Medicine (NLM) and the National Institutes of Health (NIH) find some great scientific evidences showing that Gymnema sylvestre can be helpful in controlling blood glucose levels in people with type I and type II diabetes when used in combination with insulin and other medications as prescribed by a doctor. It is important that people with existing blood glucose issues talk to their doctors before adding Gymnema sylvestre to their diet, as insulin or other medications may require to be reduced.
In healthy adults Gymnema sylvestre is said to be helping curb cravings for sweets. Though not a miraculous matter, when taken with a high-carbohydrate meal or a meal high in sugar, it can aid the body by passing through sugars and making carbs available for burning, rather than converting them into unwanted fat storage. In this way the herb will help to build lean muscle mass.
Supporters of Gymnema sylvestre opine that the herb will also lower down triglycerides and “bad cholesterol.” The NLM and NIH acknowledge that preliminary human studies with patients having type II diabetes incline to back such claim, but it may require stronger research before a determination can be positively made.
Along with a healthy and proper diet and exercise, Gymnema sylvestre may be a helpful addition to the weight-loss plan in people suffering from obesity. One should note that the herb builds up in the system over a few weeks time becoming more effective. Since it is advocated that Gymnema sylvestre be taken with each meal, it is better to get a lower-mg capsule that can be taken thrice a day to reach the full daily suggested dose. Apart from purchasing it as a stand-alone, it is also commonly available in natural weight-loss products, often with Ayurvedic herb called guggulu.
Gymnema sylvestre has been viewed as very safe herb for adults at suggested doses. If a person is pregnant or lactating, she should not take this herb due to lack of research and potential impact on the fetus. Those people who have allergies to the milkweed family may experience allergic reactions to Gymnema sylvestre too. As always, one should check with a doctor before beginning a new health routine, particularly if one is diabetic or prone to issues involving blood glucose.
Gymnema sylvestre is an extensive, much-branched, twining shrub. The herb’s leaves measure 3-6 x 2-3 cm and they are ovate or elliptic-oblong in shape with apiculate and rounded at base, sub-coriaceous.
Gymnema’s flowers are minute, greenish-yellow, spirally arranged in lateral pedunculate or nearly sessile cymes. Corolla lobes imbricate. Follicles are solitary, up to 8 x 0.7 cm in measurement, terete, lanceolate, straight or slightly curved and glabrous. The herb’s seeds are ovate-oblong, glabrous, winged, brown. The Gymnema has flowering in August-March and fruiting in the winter season.
A 52-week study of oral-repeated-dose toxicity for the extraction powder of Gymnema sylvestre, Indian-native genus, Metaplexis japonica, was conducted in both genders of Wistar rats. The rats were administered a graded dose of Gymnema sylvestre at 0.01, 0.10 and 1.00% of basal powder diet, along with a group fed solely with the basal powder diet without gymnema, for 52 weeks. General conditions were recorded daily. Body weights and food consumptions were recorded weekly up to 12 weeks, and thereafter at longer intervals. At 26 weeks, for an intermediate examination, and 52 weeks, for the final examination, animals were subjected to hematology, serum chemistry, and pathological examination. None of the animals died in the period up to 52 weeks. No exposure-related changes in body-weight, in the food consumption, in the hematological examinations, or in the serum biochemical examinations were recognized. No histopathological alterations were seen. Thus, it was concluded that there was no toxic effect in rats treated with Gymnema at up to 1.00% in the diet for 52 weeks. The no-observable-effect level from this study is 1.00% Gymnema sylvestre, i.e., 504 mg/kg/day for male and 563 mg/kg/day for female as mean daily intake, for 52 weeks (Gymnema sylvestre leaf extract: a 52-week dietary toxicity study in Wistar rats Center for Biological Safety and Research, National Institute of Health Sciences: 1-18-1, Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan).
Extract of Gymnema sylvestre R. Br leaves was orally administered once a day to rats fed a high fat diet or normal fat diet for 3 weeks to investigate its influence on lipid metabolism. As a result, Gymnema sylvestre did not influence body weight gain or feed intake in both diet groups during the experimental period. The apparent fat digestibility was significantly decreased by Gymnema sylvestre in both diet groups for the last 2 weeks of the experimental period, though not the apparent protein digestibility. In addition, the excretion of neutral sterols and acid steroids into feces was increased by Gymnema sylvestre in both diet groups. Furthermore, Gymnema sylvestre decreased the total cholesterol and triglyceride levels in serum. On the other hand, blood lecithin-cholesterol acyltransferase (LCAT) activity was increased by Gymnema sylvestre. Moreover, it was suggested that Gymnema sylvestre influenced cecal fermentation and that propionic acid and acetic acid contents in cecum were significantly increased by Gymnema. Consequently, it was suggested that Gymnema improved serum cholesterol and triglyceride levels through influence over a wide range of lipid metabolism in rats (Effect of administration with the extract of Gymnema sylvestre R. Br leaves on lipid metabolism in rats. Biol Pharm Bull. 2001 Jun;24(6):713-7).
The effectiveness of GS4, an extract from the leaves of Gymnema sylvestre, in controlling hyperglycaemia was investigated in 22 Type 2 diabetic patients on conventional oral anti-hyperglycaemic agents. Gymnema (400 mg/day) was administered for 18-20 months as a supplement to the conventional oral drugs. During Gymnema supplementation, the patients showed a significant reduction in blood glucose, glycosylated haemoglobin and glycosylated plasma proteins, and conventional drug dosage could be decreased. Five of the 22 diabetic patients were able to discontinue their conventional drug and maintain their blood glucose homeostasis with Gymnema alone. These data suggest that the beta cells may be regenerated/repaired in Type 2 diabetic patients on Gymnema sylvestre supplementation. This is supported by the appearance of raised insulin levels in the serum of patients after Gymnema sylvestre supplementation ( Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. Postgraduate Institute of Basic Medical Sciences Madras, India J Ethnopharmacol 1990 Oct;30(3):295-300)
Supplement Facts:
Serving size: 2 Vegi caps
Servings per container: 30
Each 500 mg capsule contains: Guduchi
Dosage: 1-2 Capsules two times a day after meal or or as directed by your health practitioner.
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