A strong immune system enables your body to fight off diseases. However, at times, the immune system loses its natural ability to combat infections and diseases, and we get sick. To reduce the risk of diseases, our immune system should function properly. You can boost the activities of the immune cells naturally with herbs. Immuno Plus is one such herbal formulation that contains some of the most effective immune enhancing natural substances.

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A strong immune system is essential for health. It is a very complex system of the body, involving the skin, intestines, nasal mucosa, blood, lymph and many other organs and tissues. Factors that impair the immune system include nutrient deficiencies, contaminated air, water and food, unhealthful lifestyles and too much exposure to harmful microbes. Other factors that weaken the immune system are negative attitudes and emotions and the presence of toxic metals, toxic chemicals and biological toxins in the body. Others are sluggish metabolism, lack of rest and sleep, excessive stress or too much exercise. 

The road to a strong immune system, good health and the ability to fight of the infections taking out everyone else, is a simple one.

Dosage: Two Immuno Plus capsules, twice a day, after meals, could help to boost immunity. For better result, you can take Immuno Plus capsule with Wheat Grass (DeerghaU) or vitamin C (Amalaki) supplements.

Immuno Plus is developed with care by our practicing Clinical Psychologist. It is a natural, safe, and manufactured according to the highest pharmaceutical standards. Individual ingredients are well-researched and have been put to the test over the years as a complement to the help real people with real problems.

The immune system comprises of a network of specialized cells, organs and tissues that defend the body from invading microbes. The human body provides an ideal environment for the proliferation of microbes. The immune system recognizes the foreign invaders in the body and directs specialized immune cells to target the foreign substances and kill them without harming the healthy cells.

A substance that triggers immune response is known as an antigen. Microbes such as viruses are common antigens. Immune response can even be triggered when a tissue from another person is implanted in the body. Even harmless foreign bodies such as pollens might trigger immune response, leading to allergies. Abnormal immune response might cause the immune system to target specific tissues in the body, leading to autoimmune diseases.

Lymphoid organs, located throughout the body, houses white blood cells known as lymphocytes. The lymphocytes are produced in the bone marrow. The lymphocyte that the immune system employs for killing the foreign bodies in the body are known as T lymphocytes or simply T cells. The antibodies that help to prevent infections are produced by B-lymphocytes or the B cells. While the B cells target specific antigens, the T cells directly attacks infected or malignant cells. A well-coordinated immune response is ensured by the Th cells or the helper T cells that communicate with the immune cells. The immune cells secrete proteins, known as cytokines that act as chemical messengers to enable the proper functioning of the immune system.

Along with the small T and B cells, the larger white blood cells known as phagocytes digests the worn out cells and foreign particles to eliminate them from the body. Granulocytes, such as neutrophils, eosinophils and basophils, are immune cells that contain chemicals for destroying the microbes. Mast cells are another type of immune cells that are present on the linings of the respiratory tract and intestines.

The lymphocytes encounter and combat the antigens in the lymph nodes. The spleen is another prominent site where the immune cells gather and fight antigens.

A weak immune system not only increases the risk of infections, but it can also lead to fatal diseases such as cancer. The cancer cells tend to grow and multiply by defeating the body’s immune system.

Immuno Plus contains Gelidium amansii, Withania somnifera and Tinospora cordifolia that help to improve the functions of the immune cells.

Immunomodulatory effects of agents of plant origin.

Ganju L, Karan D, Chanda S, Srivastava KK, Sawhney RC, Selvamurthy W.

Immunomodulation Laboratory, Defence Institute of Physiology and Allied Sciences

The immunomodulatory properties of amla (Emblica officinalis) and shankhpushpi (Evolvulus alsinoides) were evaluated in adjuvant induced arthritic (AIA) rat model. Injecting Complete Freund's Adjuvant (CFA) in right hind paw of the animals induced inflammation. The crude extracts of both the herbs were administered intraperitonially following a repeated treatment profile. The anti-inflammatory response of both the extracts was determined by lymphocyte proliferation activity and histopathological severity of synovial hyperplasia. Both the extracts showed a marked reduction in inflammation and edema. At cellular level immunosuppression occurred during the early phase of the disease. There was mild synovial hyperplasia and infiltration of few mononuclear cells in amla or shankhpushpi treated animals. The induction of nitric oxide synthase (NOS) was significantly decreased in treated animals as compared to controls. These observations suggest that both the herbal extracts caused immunosuppression in AIA rats, indicating that they may provide an alternative approach to the treatment of arthritis.

Immunomodulatory activity of Withania somnifera (Ashwagandha)

Davis L, Kuttan G.

Amala Cancer Research Centre

Administration of an extract from the powdered root of the plant Withania somnifera was found to stimulate immunological activity in Babl/c mice. Treatment with five doses of Withania root extract (20 mg/dose/animal; i.p.) was found to enhance the total WBC count (17125 cells/mm(3)) on 10th day. Bone marrow cellularity (27x10(6) cells/femur) as well as alpha-esterase positive cell number (1800/4000 cells) also increased significantly (P<0.001) after the administration of Withania extract. Treatment with Withania extract along with the antigen (SRBC) produced an enhancement in the circulating antibody titre and the number of plaque forming cells (PFC) in the spleen. Maximum number of PFC (985 PFC/10(6) spleen cells) was obtained on the fourth day. Withania extract inhibited delayed type hypersentivity reaction in mice (Mantoux test). Administration of Withania extract also showed an enhancement in phagocytic activity of peritoneal macrophages (76.5 pigmented cells/200) when compared to control (31.5/200 cells) in mice. These results confirm the immunomodulatory activity of W. somnifera extract, which is a known immunomodulator in indigenous medicine.

Immunomodulatory and antitumor actions of medicinal plant Tinospora cordifolia are mediated through activation of tumor-associated macrophages.

Singh N, Singh SM, Shrivastava P.

School of Biotechnology, Banaras Hindu University

The present investigations were under taken to study whether the tumor-associated macrophages (TAM) of Dalton's lymphoma (DL), a spontaneous transplantable T cell lymphoma, can be activated by the alcoholic extract of medicinal plant Tinospora cordifolia (ALTC). Intraperitoneal administration of ALTC in DL-bearing mice not only augments the basic function of macrophages such as Phagocytosis as well as their antigen presenting ability and secretion of IL-1, TNF and RNI. The results of the present investigation also indicate that the intraperitoneal administration of ALTC slow down the tumor growth and increases the life span of tumor bearing host, thus showing its anti tumor effect through destabilizing the membrane integrity of DL cells directly or indirectly. This is the first study of it's kind regarding the effect of alcoholic extract of Tinospora cordifolia on the activation of tumor associated macrophages and showing the antitumor effect on the spontaneous T-cell lymphoma (DL), thus may have clinical implications.

PMID: 15106739 [PubMed - indexed for MEDLINE]

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You can avoid those bothersome cold, cough and flu or reduce the intensity of the infections by building a strong immune system. To enhance the functions of the components of the immune system, you should provide them the right nourishment. Studies suggest that vitamins A, B6, C, D and E and minerals such as zinc, selenium, and copper might help to activate the immune cells.

Retinoic acid, the metabolite of vitamin A, improves mucosal immunity. It plays an important role in regulating development of macrophages, neutrophils, dendritic cells and lymphoid cells. (Kim CH. “Retinoid acid, immunity, and inflammation.” Vitam Horm. 2011; 86:83-101).

Vitamin D acts as an immunomodulator. Low levels of serum vitamin D might increase the risk of lung diseases. It reduces the risk of infectious diseases and inflammatory conditions by regulating the functions of lymphocytes, dendritic cells, monocytes and epithelial cells. (Herr C, Greulich T, Kocsulla RA, Meyer S, Zakharkina T, Branscheidt M, Eschmann R, Bals R. “The role of vitamin D in pulmonary disease: COPD, asthma, infection and cancer.” Respir Res. 2011 Mar 18;12:31). Hence, to strengthen the immune system, you might consider spending some minutes in the sun.

Low serum vitamin C deficiency increases the risk of infections. Studies suggest that vitamin C helps to improve the response of T cells. (Kennes B, Dumont I, Brohee D, Hubert C, Neve P. “Effect of vitamin C supplements on cell-medicated immunity in old people” Gerontology. 1983;29(5):305-10).

Vitamin E is the most important antioxidant in the human body. It is needed for sustaining the normal activities of the immune cells. Deficiency of this antioxidant vitamin adversely affects the functions of the T cells and B cells. Vitamin E protects the immune cells from oxidative damage. The antioxidant effect of the micronutrient might reduce the risk of cancers. (Pekmezci D. “Vitamin E and immunity.” Vitam Horm. 2011;86:179-215).

Vitamin B6 deficiency is frequently associated with immunodeficiency. This B vitamin helps to boost production of lymphocytes. (Bierwirth J, Ulbricht KU, Schmidt RE, Witte T. “Association of common variable immunodeficiency with vitamin B6 deficiency.” Eur J Clin Nutr. 2008 Mar;62(3):332-5).

The therapeutic function of zinc in preventing infections has been demonstrated in several studies. It could be beneficial in treating diarrhea, common cold, tuberculosis, acute lower respiratory tract infections, chronic hepatitis C and pneumonia. (Prasad AS. “Zinc: role in immunity, oxidative stress and chronic inflammation.” Curr Opin Clin Nutr Metab Care. 2009 Nov;12(6):646-52).

Selenium is needed for the synthesis of antioxidant enzymes. It plays an important role in regulating immune function. It might be beneficial for HIV positive or AIDS patients. Selenium might even reduce the risk of cancers. (Ryan-Harshman M, Aldoori W. “The relevance of selenium to immunity, cancer, and infectious/inflammatory diseases.” Can J Diet Pract Res. 2005 Summer;66(2):98-102).