Other Ingredients: Capsule (vegetable cellulose), 100% vegetarian. No fillers, binders or common allergens.

Contains No: Sugar, salt, Artificial Colour, Yeast, Gluten, Wheat or dairy products.

Main ingredients in Rencare:

Crataeva nurvala (Varuna): Crataeva nurvala could protect the kidney cells from toxic substances. Laboratory studies have shown that the phytochemical lupeol present in the herb could improve the function of the kidneys in animals with nephrotoxicity. It reduces the levels of blood urea nitrogen and creatinine. Abnormally high levels of these compounds are common symptoms of chronic kidney disease or kidney failure. Lupeol extracted from the bark of Crataeva nurvala could stimulate secretion of antioxidant enzymes, enhancing the natural antioxidant defense mechanism of the system. (Shirwaikar A, Setty M, Bommu P. “Effect of lupeol isolated from Crataeva nurvala Buch.-Ham. stem bark extract against free radical induced nephrotoxicity in rats”. Indian J Exp Biol. 2004 Jul;42(7):686-90).

Intake of Crataeva nurvala bark decoction helps to inhibit secretion of the liver enzyme glycolate oxidase associated with synthesis of oxalate stones in the kidneys. Studies indicate that the herbal decoction could reduce magnesium excretion in animals with urinary stones. Magnesium is necessary for preventing kidney diseases. (Varalakshmi P, Shamila Y, Latha E. “Effect of Crataeva nurvala in experimental urolithiasis”. J Ethnopharmacol. 1990 Mar;28(3):313-21). Lupeol extracted from the bark of the herb could increase excretion of oxalates through the urine, which significantly lowers the risk of developing kidney stones associated with low levels of citrate and glycosaminoglycans. Intake of crataeva nurvala bark extract even helps to bring down the levels of enzymes linked to renal tissue damage. (Malini MM, Baskar R, Varalakshmi P. “Effect of lupeol, a pentacyclic triterpene, on urinary enzymes in hyperoxaluric rats.” Jpn J Med Sci Biol. 1995 Oct-Dec;48(5-6):211-20).

Boerhavia diffusa (Punarnava): Formation of calcium oxalate stones might be prevented with Boerhavia diffusa. Findings from experimental studies indicate that the plant extract could gradually reduce the size of the calcium oxalate crystals. In laboratory studies, the calcium oxalate stones completely disappeared with administration of high doses of the herb. In addition, the diuretic action of the herb encourages elimination of calcium oxalate crystals by increasing the volume of urine formation. (Yasir F, Wagar MA. “Effect of indigenous plant extracts on calcium oxalate crystallization having a role in urolithiasis.” Urol Res. 2011 Jun 4).

Tribulus terrestris (Gokshur): Tribulus terrestris, commonly called gokhru or gokshur could be used as an alternative to the present day treatment of recurrent kidney stones. Devoid of adverse side effects, treatment with Tribulus terrestris plant extract might impair development of calcium oxalate stones and might reduce the size of the renal stones. This plant extract can even prevent injuries to the renal tissues from exposure to the oxalate stones. Tribulus terrestris extract could inhibit secretion of the enzymes associated with kidney malfunction. (Aggarwal A, Tandon S, Singla SK, Tandon C. “Diminution of oxalate induced renal tubular epithelial cell injuriy and inhibition of calcium oxalate crystallization in vitro by aqueous extract of Tribulus terrestris.” Int Braz J Urol. 2010 Jul-Aug;36(4):480-8). Studies indicate that the fruit extract of Tribulus terrestris could protect the kidneys from toxic substances. (Kavitha AV, Jagadeesan G. “Role of Tribulus terrestris (Linn.) (Zygophyllacea) against mercuric chloride induced nephrotoxicity in mice, Mus musculus (Linn.)” J Environ Biol. 2006 May;27(2 Suppl);397-400). Saponins present in the herb might prevent growth of cancer cells in the kidneys. (Yang HJ, Qu WJ, Sun B. “Experimental study of saponins from Tribulus terrestris on renal carcinoma cell line.” Zhongguo Zhong Yao Za Zhi. 2005 Aug;30(16):1271-4).

Bergenia ligulata (Pashanbhed): In South Asia, Bergenia ligulata rhizome is widely used for treating urinary stones. While evaluating the effectiveness of the rhizome in healing kidney stones, researchers found that Bergenia ligulata rhizome extract could obstruct calcium oxalate crystallization. The herb possesses antioxidant property. It acts as a diuretic. By increasing the urine output, Bergenia ligulata helps to flush out the calcium oxalate crystals from the urinary tract. (Bashir S, Gilani AH. “Antiurolithic effect of Bergenia ligulata rhizome: An explanation of the underlying mechanisms.” J Ethnopharmacol. 2009 Feb 25;122(1):106-16).

Other ingredients: The effectiveness of the potent anti-urolithic herbal formulation is further augmented with Santalum album (chandana safed), Cinnamomum camphora (karpur), Elettaria cardamomum (Ela) and Hordeum vulgare ash (yavkshar). In Ayruveda, they are recommended for treating urinary and kidney problems. They are used by folk healers for flushing out kidney stones, easing urination, treating burning sensation during urination, reducing painful urination and treating inflammation and bleeding in the kidneys. (Ballabh B, Chaurasia OP, Ahmed Z, Singh SB. “Traditional medicinal plants of cold desert Ladakh used against kidney and urinary disorders.” J Ethnopharmacol. 2008 Jul 23;118(2):331-9).