Morpheme Guduchi (Tinospora Cordifolia)
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GUDUCHI MAIN INGREDIENT
Tinospora Cordifolia or Guduchi is a popular herb that helps in managing the immune system and might help in providing relief from a number of diseases. The herb has a special mention in the traditional Ayurveda because of its unique properties, which helps in combating infections. The supplements of Guduchi play an important role in the rejuvenation of body cells and improve the functions of macrophages, which in turn helps in enhancing the immunity system in the body. Tinospora cordifolia could help in reducing abdominal discomfort caused by inflammation of the lining of the inner wall of the abdomen following infections by E. coli bacteria species.
BENEFITS OF MORPHEME GUDUCHI
The extract of this herb has been proved clinically to support recovery from ulcerative colitis and is considered beneficial for patients with breast cancer who are undergoing chemotherapy. Various health advocates have lauded the health benefits of this herbal plant for many years. Recently, a placebo-controlled, double-blind, randomized clinical study was carried out to prove scientifically the effectiveness of the extract obtained from the herbal plant. A research article published in the ‘Scandinavian Journal of Gastroenterology’ in the year April 2002 reported that the patients, who were diagnosed clinically with distal-ulcerativ-colitis, were given 100 cc of the extract or a placebo. This was continued for a month and the participants maintained a diary. The clinicians examined the changes in patients. After the completion of the study, it was noted that all the patients showed significant decrease in disease activity.
HOW IS MORPHEME GUDUCHI USEFUL
According to the latest report, a substance known as arabinogalacctan polysaccharide from the stem of the plant is known to stimulate tolerance against endotoxic-shock via modulation of nitric oxide and cytokines. Besides, nitric oxide is released by marine macrophages through modulation. The immunomodulatory property of the plant is used as an adjuvant-therapy to aid recovery from foot ulcers in diabetic patients. In a double-blind randomized study that had 50 patients, the herb was administered for about 18 months, which produced considerably better results with enhancement in wound healing. This indicates the beneficial property of immunomodulation in healing ulcers. Biological activities of plant’s crude extracts from various parts of bark, fruit, stem, root and leaf have been reported. In addition, the effect of Immunostimulatory of the leaf extract on Neutrophil activity (non-specific immunity), Antibody response (specific immunity) and disease resistance against the bacterium Aeromonas hydrophila is reported in Oreochoromis mossambicus.
SEVERAL HEALTH BENEFITS OF MORPHEME GUDUCHI
Besides, the extract of the leaf can be used as an immunoprophylactic, which helps in averting diseases in finfish-aquaculture. Guduchi’s methanolic extract has protective outcome against shrimp-viral-pathogenesis because of its immunomodulatory action. The animals fed with this extract showed very less infection of white-spot-syndrome virus. In hepatitis patients, the herb has shown normalization in the functions of the liver and in rhinitis patients, it showed significant reduction in the signs of allergic rhinitis. The pre-clinical studies of the herb has shown diverse pharmacological activities such as immunobiological activity, hypolipidaemic, digestive, antiulcer, anti-stress, antioxidant, anti-inflammatory, hypoglycemic, anti-diabetic and anti-cancer activity. The reports have shown that guduchi can benefit people suffering from uraemia, urinary calculi, mental disorders and liver disorders.
DIRECTION FOR USE
Take 1 Veg Capsule 1-2 Times a Day after meals or as directed by healthcare professional.
What is Morpheme Guduchi?
Morpheme Guduchi contains the extract of high-quality Guduchi herb in the capsule form. The processing is done using the latest technology in order to make sure that the product reaches the consumers in pure and untainted form.
What is Guduchi?
Guduchi also known as Tinospora Cordifolia is an herbaceous vine, which is mostly found in the tropical regions of India, Sri Lanka and Myanmar. The herb is known to strengthen the body’s immune system and decreases the susceptibility of the body to common infections.
When will I get to see the results?
The significant results of the product is noticed anywhere from four to six weeks. However, it may vary depending on various factors like metabolism and present health.
IngredientsServing size: 1 Veg capsule Servings per container: 60 Each 500 mg capsule contains: Guduchi Each Bottle Contains: 60 Vegi Caps Suggested Usage: 1 Capsule twice daily after meals.
|Serving Size: 1 Veg Capsule||
Amount Per Serving
% Daily Value
|Guduchi (Tinospora cordifolia) (Stem) Extract||500mg.||**|
|** Daily value not established|
How Tinospora cordifolia acts as immunity booster
Tinospora cordifolia is an important medicinal plant in Ayurveda. Its strong immunomodulatory effect helps to improve the body’s resistance to infections. The efficacy of the herb in strengthening the immune system has been demonstrated in several studies.
Helps in boosting immunity
The immune stimulatory affect of Tinospora cordifolia reduces the risks of infections. The active compounds in the herb help to activate the natural killer cells or the lymphocytes. Intake of the herb significantly improves the functions of the T cells and the B cells. It also improves cytokine and helper T cells production and supports macrophage activation. Hence, by improving the overall function of the immune system, Tinospora cordifolia protects the body from microbes. (Nair PK, Rodriquez S, Ramachandran R, Alamo A, Melnick SJ, Escalon E, Garcia PL Jr, Wnuk SF, Ramachandran C. “Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia.” Int Immunopharmacol. 2004 Dec 15;4(13):1645-59).
Despite activating and increasing the production of cytokines for improving immunity, Tinospora cordifolia does not support overproduction of the pro-inflammatory proteins. Excess production of cytokines leads to inflammatory conditions. The immunomodulatory effect of the medicinal plant improves the activities of the components of the immune system without causing abnormal immune response owing to heightened production of pro-inflammatory immune components. (Raghu R, Sharma D, Ramakrishna R, Khanam S, Chintalwar GJ, Sainis KB. “Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia.” Immunol Lett. 2009 Mar 24;123(1):60-71).
Cholestasis or obstruction of bile flow from the liver suppresses activities of immune cells. People suffering from this condition are susceptible to infections. Studies suggest that Tinospora cordifolia could improve the immunity in people suffering from obstructive jaundice that blocks bile flow. (Rege NN, Nazareth HM, Bapat RD, Dahanukar SA. “Modulation of immunosuppresion in obstructive jaundice by Tinospora cordofolia.” Indian J Med Res. 1989 Dec;90:478-83).
Helps in reducing fungal infections
Tinospora cordifolia could also be effective for Candia infections. (Rege NN, Dahanukar SA. “Quantitation of microbicidal activity of mononuclear phagocytes: an in vitro technique.” J Postgrad Med. 1993 Jan-Mar;39(1):22-5).
Beneficial for HIV positive patients
Clinical trials with Tinospora cordifolia indicate the effectiveness of the herb in improving immunity in human immuno-deficiency virus (HIV) positive patients. In about 60% HIV positive patient, intake of Tinospora cordifolia extract reduced the various symptoms of the disease. Scientists suggest Tinospora cordifolia therapy as an adjunct to management of HIV or AIDS. (Kalikar MV, Thawani VR, Varadpande UK, Sontakke SD, Singh RP, Khiyani RK. “Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients.” Indian J Pharmacol. 2008 Jun;40(3):107-10).
Helps in slowing down tumor growth
The anti-tumor effect of Tinsopora cordifolia has been proved in experimental studies. It could slow down tumor growth and improve the life span of tissues bearing the tumor. (Singh N, Singh SM, Shrivastava P. “Immunomodulatory and antitumor actions of medicinal plant Tinospora cordifolia are mediated through activation of tumor-associated macrophages.” Immunopharmacol Immunotoxicol. 2004 Feb;26(1):145-62).
Helps in improving wound healing
Slow wound healing and poor immunity increase the risk of infections. The risk of developing wound sores is greater among diabetics. The immunomodulation effect of Tinospora cordifolia helps to speed up the wound healing process and helps to eradicate bacteria present at the site of the wound by activating the phagocytes. (Purandare H, Supe A. “Immunomodulatory role of Tinospora cordifolia as an adjuvant in surgical treatment of diabetic foot ulcers: a prospective randomized controlled study.” Indian J Med Sci. 2007 Jun;61(6):347-55).
Functions as an antioxidant
The antioxidant effect of Tinospora cordifolia protects the body from chemotoxicity caused by chemicals produced by the scavenging activities of free radicals. It helps to protect the immune system from free radicals as evident from the improved activities of white blood cells and bone marrow cells following use of Tinospora cordifolia extract. (Mathew S, Kuttan G. “Antioxidant activity of Tinospora cordifolia and its usefulness in the amelioration of cyclophosphamide induced toxicity.” J Exp Clin Cancer. 1997 Dec;16(4):407-11). The antioxidant effect of the herb coupled with its chemopreventive function against carcinogens helps in improving the effectiveness of Tinospora cordifolia as an adjuvant for cancer treatment. (Singh RP, Banerjee S, Kumar PV, Raveesha KA, Rao AR. “Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibit lipid peroxidation in mice.” Phytomedicine. 2006 Jan;13(1-2):74-84).
1. A study was carried out to have evaluation of the anti-neoplastic activity of Guduchi (Tinospora cordifolia) in Ehrlich ascites carcinoma bearing mice. It carried out positive results on mice. (Department of Radiobiology, Kasturba Medical College, Manipal, India by Jagetia GC, Rao SK. in Biol. Pharm. Bull. 2006 Mar;29(3):460-6)
2. The antioxidant property of T. cordifolia roots was studied by administering the aqueous extract to alloxan-induced diabetic rats. After six weeks, the levels of plasma thiobarbituric acid reactive substances, ceruloplasmin, and alpha-tocopherol were drastically decreased. In addition, the levels of glutathione and vitamin C were elevated. The root extract at a dose of 5 g/kg was the most effective.